Course Content
Introduction to Biostatistics and R
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Descriptive Statistics and Exploratory Data Analysis
Hypothesis Testing and Statistical Inference
Hypothesis Testing and Statistical Inference
Hypothesis Testing and Statistical Inference
Survival Analysis and Clinical Trial Design
Bioinformatics and Genomic Data Analysis
Reproducible Research with R Markdown
Biostatistics with R
About Lesson

Introduction to Biostatistics

  • Biostatistics defined: Explain that biostatistics is the application of statistical methods to biological and medical data.
  • Importance of biostatistics: Discuss how biostatistics plays a crucial role in generating insights, making evidence-based decisions, and advancing research in the life sciences field.
  • Applications of biostatistics: Highlight various examples of biostatistical analyses in healthcare, epidemiology, genetics, and clinical trials.

Introduction to R

  • R programming language: Introduce R as a popular statistical programming language widely used in biostatistics and data analysis.
  • Advantages of R: Discuss the benefits of using R, such as its open-source nature, extensive statistical libraries, and active user community.
  • Comparison with other software: Mention other statistical software packages like SPSS and SAS, but emphasize the flexibility and customization options offered by R.

Installing R and RStudio

  • R installation: Provide step-by-step instructions on how to download and install R on different operating systems (Windows, macOS, Linux).
  • RStudio installation: Explain the importance of using an integrated development environment (IDE) and guide students on installing RStudio, which enhances the programming experience.
  • Verifying the installation: Show how to open RStudio and verify the successful installation.

Basic R Syntax and Data Structures

  • R as a calculator: Demonstrate how R can be used as a calculator for basic arithmetic operations and mathematical functions.
  • Variables in R: Introduce the concept of variables and how to assign values to variables in R. Explain the importance of choosing meaningful variable names.
  • Data types: Explain the different data types in R, such as numeric, character, logical, and factors.
  • Data structures: Introduce vectors, matrices, data frames, and lists as fundamental data structures in R.

Data Import and Cleaning in R

  • Data import: Discuss the importance of data import and demonstrate how to load data from different file formats, such as CSV, Excel, and text files, using R functions like read.csv() and read.table().
  • Exploring data: Introduce functions like head() and summary() to explore the loaded dataset and gain insights into its structure and summary statistics.
  • Handling missing values: Explain the significance of missing data and discuss methods for identifying and dealing with missing values in the dataset using R.

Introduction to Data Visualization in R

  • Principles of effective data visualization: Emphasize the importance of visualizing data to understand patterns, relationships, and distributions.
  • Basic plotting functions: Introduce common plotting functions in R, such as plot(), hist(), and boxplot(), to create basic visualizations.
  • ggplot2 package: Briefly mention the ggplot2 package, a powerful tool for creating more advanced and customizable visualizations in R.
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